The Diversity of Deep-Sea Actinobacteria and Their Natural Products: An Epitome of Curiosity and Drug Discovery

Bioprospecting of novel antibiotics has been the conventional norm research fostered by researchers worldwide to combat drug resistance. With exhaustion incessant leads, search for new chemical entities moves into uncharted territories such as deep sea. The sea is a furthermost ecosystem with much untapped biodiversity thriving under extreme conditions. Accordingly, it also encompasses vast pool ancient natural products. Actinobacteria are frequently regarded bacteria interest due their inherent antibiotic-producing capabilities. These interesting groups occupy diverse ecological habitats including multitude different deep-sea habitats. In this review, we provide recent update on species and compounds actinomycetes from environments within period 2016–2022. Within period, total 24 were discovered characterized well 101 various biological activities. microbial communities ecosystems emerging frontiers bioprospecting.